WORLD (Enmaeya News) - November 15, 2025
New findings from a clinical trial challenge long-standing advice that individuals with atrial fibrillation (AFib) should avoid coffee. The study suggests that drinking one cup of caffeinated coffee daily may significantly lower the risk of recurrent heart rhythm disturbances in people with a history of AFib or atrial flutter.
The DECAF Trial
The six-month trial, called the DECAF Trial (“Does Eliminating Coffee Avoid Fibrillation?”), enrolled 200 adults with a prior history of AFib or atrial flutter. Participants were randomly assigned to either consume at least one cup of caffeinated coffee daily or avoid caffeine entirely.
Results showed that 47% of participants who continued daily coffee intake experienced a recurrence of AFib or flutter, compared with 64% in the caffeine-abstaining group, a 39% lower risk of recurrence for coffee drinkers. Participants had an average age of 69, with 71% male. All had undergone cardioversion to restore normal rhythm before the trial.
The trial was published in JAMA on November 9, 2025, and presented at the American Heart Association (AHA) Scientific Sessions.
Implications for Patients and Clinicians
Caffeine has traditionally been restricted in patients with arrhythmias due to its stimulant effects. However, this study suggests moderate, habitual coffee consumption may be safe and even protective for certain AFib patients. Senior author Gregory M. Marcus of the University of California, San Francisco, said, “Caffeinated coffee may not be responsible for raising the risk of AFib and may even reduce it.”
Researchers suggested several possible reasons for the protective effect. Caffeine may block adenosine receptors, which can help stabilize the heart rhythm. Coffee also contains antioxidants and anti-inflammatory compounds, such as chlorogenic acids, which could reduce arrhythmia triggers. Additionally, habitual coffee drinkers in the study were more physically active, suggesting that lifestyle factors may also contribute.
Takeaway
For patients with AFib who enjoy coffee, the study offers reassurance that a daily cup of caffeinated coffee may be safe and could reduce the likelihood of recurrent irregular heart rhythms. Doctors may consider advising moderate coffee consumption as part of individualized care.
